Efficacy, Pharmacokinetics, and Toxicity Profiles of a Broad Anti-SARS-CoV-2 Neutralizing Antibody

Efficacy, Pharmacokinetics, and Toxicity Profiles of a Broad Anti-SARS-CoV-2 Neutralizing Antibody

We recently reported the isolation and characterization of an anti-SARS-CoV-2 antibody, called IgG-A7, that protects transgenic mice expressing the human angiotensin-converting enzyme 2 (hACE-2) from an infection with SARS-CoV-2 Wuhan. We show here that IgG-A7 protected 100% of the transgenic mice i...

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Bibliographic Details
Main Authors: Silvia Godínez-Palma, Edith González-González, Frida Ramírez-Villedas, Circe Garzón-Guzmán, Luis Vallejo-Castillo, Gregorio Carballo-Uicab, Gabriel Marcelín-Jiménez, Dany Batista, Sonia M. Pérez-Tapia, Juan C. Almagro
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Viruses
Subjects:
COVID-19
therapeutic antibody
SARS-CoV-2 Delta
SARS-CoV-2 Omicron
toxicology
Online Access:https://www.mdpi.com/1999-4915/15/8/1733

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https://www.mdpi.com/1999-4915/15/8/1733

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