Combined Action of Shiga Toxin Type 2 and Subtilase Cytotoxin in the Pathogenesis of Hemolytic Uremic Syndrome

Shiga toxin-producing <i>E. coli</i> (STEC) produces Stx1 and/or Stx2, and Subtilase cytotoxin (SubAB). Since these toxins may be present simultaneously during STEC infections, the purpose of this work was to study the co-action of Stx2 and SubAB. Stx2 + SubAB was assayed in vitro on mon...

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Bibliographic Details
Main Authors: Romina S. Álvarez, Fernando D. Gómez, Elsa Zotta, Adrienne W. Paton, James C. Paton, Cristina Ibarra, Flavia Sacerdoti, María M. Amaral
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/13/8/536