Investigation of Serum Levels and Activity of Matrix Metalloproteinases 2 and 9 (MMP2, 9) in Opioid and Methamphetamine-Dependent Patients

Investigation of Serum Levels and Activity of Matrix Metalloproteinases 2 and 9 (MMP2, 9) in Opioid and Methamphetamine-Dependent Patients

Matrix metalloproteinases (MMPs) are a group of zinc-dependent proteolytic enzymes that play a role in extracellular matrix (mainly collagen) degradation and remodeling. MMPs are not only causes of the increase rewarding effects of drugs, but also act as pro-addictive agents. In this research, 22 mo...

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Bibliographic Details
Main Authors: Khadijeh Najafi, Daniel Elieh Ali Komi, Habibolah Khazaie, Ali Moini, Asad Vaisi-Raygani, Hamid Reza Ahmadi, Mohammad Rasoul Ghadami, Amir Kiani
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2018-12-01
Series:Acta Medica Iranica
Subjects:
Drug dependence
Matrix metalloproteinase
Morphine
Methamphetamine
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/7396

Internet

https://acta.tums.ac.ir/index.php/acta/article/view/7396

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