Holistic Approach to Immune Checkpoint Inhibitor-Related Adverse Events

Holistic Approach to Immune Checkpoint Inhibitor-Related Adverse Events

Immune checkpoint inhibitors (ICIs) block inhibitory molecules, such as cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), programmed cell death protein 1 (PD-1), or its ligand, programmed cell death protein ligand 1 (PD-L1) and enhance antitumor T-cell activity. ICIs provide clinical benefits in...

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Bibliographic Details
Main Authors: Remo Poto, Teresa Troiani, Gjada Criscuolo, Giancarlo Marone, Fortunato Ciardiello, Carlo Gabriele Tocchetti, Gilda Varricchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Immunology
Subjects:
cancer
cytotoxic T lymphocyte-associated protein (CTLA-4)
immunotherapy
immune checkpoint inhibitor (ICI)
immune-related adverse event (irAE)
programmed cell death protein -1 (PD-1)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.804597/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.804597/full

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