Prediction of recombinant Mycobacterium tuberculosis α-crystallin oligomer chaperone activity using polynomial graphs [version 1; peer review: 2 approved]

Background: Mycobacterial α-crystallin (Acr) is a chaperone that prevents misfolding of proteins when Mycobacterium tuberculosis is found in a latent form in the host tissue. Methods: Using insulin as a model substrate and utilizing polynomial graphs, we attempted to predict molecular-level interact...

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Bibliographic Details
Main Authors: Gautam Krishnan, Utpal Roy
Format: Article
Language:English
Published: F1000 Research Ltd 2018-11-01
Series:F1000Research
Online Access:https://f1000research.com/articles/7-1801/v1