Mir-573 regulates cell proliferation and apoptosis by targeting Bax in human degenerative disc cells following hyperbaric oxygen treatment

Mir-573 regulates cell proliferation and apoptosis by targeting Bax in human degenerative disc cells following hyperbaric oxygen treatment

Abstract Background MicroRNA (miRNA) plays a vital role in the intervertebral disc (IVD) degeneration. The expression level of miR-573 was downregulated whereas Bax was upregulated notably in human degenerative nucleus pulposus cells. In this study, we aimed to investigate the role of miR-573 in hum...

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Bibliographic Details
Main Authors: Song-Shu Lin, Chi-Chien Niu, Li-Jen Yuan, Tsung-Ting Tsai, Po-Liang Lai, Kowit-Yu Chong, Kuo-Chen Wei, Chiung-Yin Huang, Meng-Ling Lu, Chuen-Yung Yang, Steve W. N. Ueng
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
MicroRNA-573
Bax
Caspase
HBO
NP
Online Access:https://doi.org/10.1186/s13018-020-02114-6

Internet

https://doi.org/10.1186/s13018-020-02114-6

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