Calcium, synaptic plasticity and intrinsic homeostasis in Purkinje neuron models

We recently reproduced the complex electrical activity of a Purkinje cell (PC) with very different combinations of ionic channel maximum conductances, suggesting that a large parameter space is available to homeostatic mechanisms. It has been hypothesized that cytoplasmic calcium concentrations cont...

Full description

Bibliographic Details
Main Authors: Pablo Achard, Erik De Schutter
Format: Article
Language:English
Published: Frontiers Media S.A. 2008-12-01
Series:Frontiers in Computational Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/neuro.10.008.2008/full