Rapid and sensitive quantification of efavirenz in rat plasma using HPLC-MS/MS method

This article aims to analyze the development of a rapid and sensitive HPLC–MS/MS method for quantification of efavirenz in rat plasma. The developed method included a liquid-liquid extraction process with methyl-tert-butyl ether solution, where hydrochlorothiazide was used as internal standard. The...

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Bibliographic Details
Main Authors: Leandro Tasso, Thamyrys Barreto Argenta, Beatriz Ferreira de Carvalho Patricio, Helvécio Vinícius Antunes Rocha
Format: Article
Language:English
Published: Universidade Federal do Rio Grande do Sul 2024-01-01
Series:Drug Analytical Research
Subjects:
Online Access:https://seer.ufrgs.br/Po/index.php/dar/article/view/137367