Hsa_circ_0066523 promotes the proliferation and osteogenic differentiation of bone mesenchymal stem cells by repressing PTEN

Hsa_circ_0066523 promotes the proliferation and osteogenic differentiation of bone mesenchymal stem cells by repressing PTEN

Aims: Circular RNAs (circRNAs) are a novel type of non-coding RNA that plays major roles in the development of diverse diseases including osteonecrosis of the femoral head (ONFH). Here, we explored the impact of hsa_circ_0066523 derived from forkhead box P1 (FOXP1) (also called circFOXP1) on bone me...

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Bibliographic Details
Main Authors: Wei Xin, Shuai Yuan, Bo Wang, Qirong Qian, Yi Chen
Format: Article
Language:English
Published: The British Editorial Society of Bone & Joint Surgery 2021-08-01
Series:Bone & Joint Research
Subjects:
circ_0066523
osteoblast differentiation
kdm5b
mesenchymal stem cells (mscs)
bmscs
rnas
staining
red s
osteoblast
western blot
osteonecrosis of the femoral head (onfh)
quantitative real-time polymerase chain reaction
phosphatase
Online Access:https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.108.BJR-2020-0127.R2

Internet

https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.108.BJR-2020-0127.R2

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