OrgaSegment: deep-learning based organoid segmentation to quantify CFTR dependent fluid secretion

OrgaSegment: deep-learning based organoid segmentation to quantify CFTR dependent fluid secretion

Abstract Epithelial ion and fluid transport studies in patient-derived organoids (PDOs) are increasingly being used for preclinical studies, drug development and precision medicine applications. Epithelial fluid transport properties in PDOs can be measured through visual changes in organoid (lumen)...

Full description

Bibliographic Details
Main Authors: Juliet W. Lefferts, Suzanne Kroes, Matthew B. Smith, Paul J. Niemöller, Natascha D. A. Nieuwenhuijze, Heleen N. Sonneveld van Kooten, Cornelis K. van der Ent, Jeffrey M. Beekman, Sam F. B. van Beuningen
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-05966-4

Internet

https://doi.org/10.1038/s42003-024-05966-4

Similar Items