Huangqi Guizhi Wuwu decoction alleviates oxaliplatin-induced peripheral neuropathy via the gut-peripheral nerve axis

Huangqi Guizhi Wuwu decoction alleviates oxaliplatin-induced peripheral neuropathy via the gut-peripheral nerve axis

Abstract Background Oxaliplatin-induced peripheral neurotoxicity (OIPN) limits the dose of chemotherapy and seriously affects the quality of life. Huangqi Guizhi Wuwu Decoction (HGWD) is a classical Traditional Chinese Medicine (TCM) formula for the prevention of OIPN. However, its specific pharmaco...

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Bibliographic Details
Main Authors: Zhengwei Zhang, Juan Ye, Xinyu Liu, Wenjing Zhao, Bing Zhao, Xuejiao Gao, Hongli Lan, Yuze Wu, Yang Yang, Peng Cao
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Chinese Medicine
Subjects:
Intestinal flora
Oxaliplatin-induced peripheral neurotoxicity
Huangqi Guizhi Wuwu decoction
Inflammation
Lipopolysaccharide
Online Access:https://doi.org/10.1186/s13020-023-00826-5

Internet

https://doi.org/10.1186/s13020-023-00826-5

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