Chronic cAMP activation induces adipocyte browning through discordant biphasic remodeling of transcriptome and chromatin accessibility

Objective: Adipose tissue thermogenesis has been suggested as a new therapeutic target to promote energy metabolism for obesity and metabolic disease. Cold-inducible thermogenic adipocytes, called beige adipocytes, have attracted significant attention for their potent anti-obesity activity in adult...

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Bibliographic Details
Main Authors: Jisun So, Solaema Taleb, Jamie Wann, Olivia Strobel, Kyungchan Kim, Hyun Cheol Roh
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Molecular Metabolism
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877822001880