Hypoxia and Ezrin Expression in Primary Melanoma Have High Prognostic Relevance

Hypoxia and Ezrin Expression in Primary Melanoma Have High Prognostic Relevance

Hypoxia affects tumor aggressiveness and activates pathways associated with epithelial mesenchymal transition (EMT) which are crucial for tumor progress. In this study, the correlation of hypoxia and EMT with sentinel lymph node status and tumor-specific survival was investigated in primary melanoma...

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Bibliographic Details
Main Authors: Umberto Maccio, Alanna Mihic, Daniela Lenggenhager, Isabel Kolm, Christiane Mittmann, Mathias Heikenwälder, Anna Lorentzen, Daniela Mihic-Probst
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
melanoma
metastasis
hypoxia
HIF-1α
tumor progression
Ezrin
Online Access:https://www.mdpi.com/1422-0067/23/18/10745

Internet

https://www.mdpi.com/1422-0067/23/18/10745

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