Heme (dys)homeostasis and liver disease

Heme is essential for a variety of proteins involved in vital physiological functions in the body, such as oxygen transport, drug metabolism, biosynthesis of steroids, signal transduction, antioxidant defense and mitochondrial respiration. However, free heme is potentially cytotoxic due to the capac...

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Bibliographic Details
Main Authors: Tiago L. Duarte, Nicole Viveiros, Catarina Godinho, Delfim Duarte
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-07-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2024.1436897/full