Stachydrine Hydrochloride Regulates the NOX2-ROS-Signaling Axis in Pressure-Overload-Induced Heart Failure

Stachydrine Hydrochloride Regulates the NOX2-ROS-Signaling Axis in Pressure-Overload-Induced Heart Failure

Our previous studies revealed the protection of stachydrine hydrochloride (STA) against cardiopathological remodeling. One of the underlying mechanisms involves the calcium/calmodulin-dependent protein kinase Ⅱ (CaMKII). However, the way STA influences CaMKII needs to be further investigated. The ni...

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Bibliographic Details
Main Authors: Shuang Lu, Yueyang Liang, Songru Yang, Mengwei Fu, Xiaoli Shan, Chen Zhang, Huihua Chen, Pei Zhao, Rong Lu
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:International Journal of Molecular Sciences
Subjects:
stachydrine hydrochloride
heart failure
nicotinamide adenine dinucleotide phosphate oxidase 2
reactive oxygen species
excitation-contraction coupling
Online Access:https://www.mdpi.com/1422-0067/24/18/14369

Internet

https://www.mdpi.com/1422-0067/24/18/14369

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