Engineering CRISPR for emerging therapeutic applications
Clustered regularly interspaced short palindromic repeats (CRISPRs) were originally identified in bacterial and archaeal genomes as an adaptive immune response against invading viruses and phages. The discovery of the ability of CRISPR–Cas9 to cut targeted DNA sequences at predetermined sites has in...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2024-12-01
|
Series: | EngMedicine |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2950489924000356 |