Structural variant-based pangenome construction has low sensitivity to variability of haplotype-resolved bovine assemblies

Structural variant-based pangenome construction has low sensitivity to variability of haplotype-resolved bovine assemblies

Pangenomes have a number of advantages over linear reference assemblies. Here the authors use bovine haplotype-resolved assemblies to show that structural variant-based pangenomes are consistent regardless of sequence platform, assembler, or coverage, suggesting that rigid protocols may not be requi...

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Bibliographic Details
Main Authors: Alexander S. Leonard, Danang Crysnanto, Zih-Hua Fang, Michael P. Heaton, Brian L. Vander Ley, Carolina Herrera, Heinrich Bollwein, Derek M. Bickhart, Kristen L. Kuhn, Timothy P. L. Smith, Benjamin D. Rosen, Hubert Pausch
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-30680-2

Internet

https://doi.org/10.1038/s41467-022-30680-2

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