Overactivation of the IGF signalling pathway in osteosarcoma: a potential therapeutic target?
Abstract Osteosarcoma is the most common primary malignant bone tumour in children and adolescents. More than a third of patients do not respond to standard therapy and urgently require alternative treatment options. Due to a high degree of inter‐ and intra‐tumoural genomic heterogeneity and complex...
Main Authors: | Baptiste Ameline, Michal Kovac, Michaela Nathrath, Maxim Barenboim, Olaf Witt, Andreas H Krieg, Daniel Baumhoer |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-03-01
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Series: | The Journal of Pathology: Clinical Research |
Subjects: | |
Online Access: | https://doi.org/10.1002/cjp2.191 |
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