Low levels of sex hormone-binding globulin predict an increased breast cancer risk and its underlying molecular mechanisms

Low levels of sex hormone-binding globulin predict an increased breast cancer risk and its underlying molecular mechanisms

Sex hormone-binding globulin (SHBG) is a serum glycoprotein exhibiting the unique feature of binding sex steroids with high affinity and specificity. Over the past few decades, there have been significant breakthroughs in our understanding of the function and regulation of SHBG. The biological role...

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Bibliographic Details
Main Authors: Zhao Shuhang, Gu Jiaojiao, Tian Yu, Wang Ruoyan, Li Wentao
Format: Article
Language:English
Published: De Gruyter 2024-02-01
Series:Open Life Sciences
Subjects:
sex hormone-binding globulin
breast cancer
endocrine therapy
transcriptomics
proteomics
endocrine drug-resistance
Online Access:https://doi.org/10.1515/biol-2022-0822

Internet

https://doi.org/10.1515/biol-2022-0822

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