Serum- and xeno-free culture of human umbilical cord perivascular cells for pediatric heart valve tissue engineering

Serum- and xeno-free culture of human umbilical cord perivascular cells for pediatric heart valve tissue engineering

Abstract Background Constructs currently used to repair or replace congenitally diseased pediatric heart valves lack a viable cell population capable of functional adaptation in situ, necessitating repeated surgical intervention. Heart valve tissue engineering (HVTE) can address these limitations by...

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Bibliographic Details
Main Authors: Shouka Parvin Nejad, Monica Lecce, Bahram Mirani, Nataly Machado Siqueira, Zahra Mirzaei, J. Paul Santerre, John E. Davies, Craig A. Simmons
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stromal cells
Human umbilical cord perivascular cells
Serum- and xeno-free culture
Extracellular matrix
Heart valve tissue engineering
Online Access:https://doi.org/10.1186/s13287-023-03318-3

Internet

https://doi.org/10.1186/s13287-023-03318-3

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