Cannabis Constituents and Acetylcholinesterase Interaction: Molecular Docking, In Vitro Studies and Association with <i>CNR1 rs806368</i> and <i>ACHE rs17228602</i>

The study documented here was aimed to find the molecular interactions of some of the cannabinoid constituents of cannabis with acetylcholinesterase (AChE). Molecular docking and LogP determination were performed to predict the AChE inhibitory effect and lipophilicity. AChE enzyme activity was measu...

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Bibliographic Details
Main Authors: Tiyyaba Furqan, Sidra Batool, Rabia Habib, Mamoona Shah, Huba Kalasz, Ferenc Darvas, Kamil Kuca, Eugenie Nepovimova, Sajida Batool, Syed M Nurulain
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/10/5/758