Embryonic bone morphogenetic protein and nodal induce invasion in melanocytes and melanoma cells

Despite recent progress in melanoma therapy via inhibition of activated oncogenes or immune stimulation, most stage IV melanoma patients still have limited survival times. Existing therapeutic approaches eventually fail to prevent further invasion and metastasis, which is driven by a morphological p...

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Bibliographic Details
Main Authors: Tobias Sinnberg, Heike Niessner, Mitchell P. Levesque, Christoph Dettweiler, Claus Garbe, Christian Busch
Format: Article
Language:English
Published: The Company of Biologists 2018-06-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/7/6/bio032656