Early Lesion of Post-Primary Tuberculosis: Subclinical Driver of Disease and Target for Vaccines and Host-Directed Therapies
The characteristic lesion of primary tuberculosis is the granuloma as is widely studied in human tissues and animal models. Post-primary tuberculosis is different. It develops only in human lungs and begins as a prolonged subclinical obstructive lobular pneumonia that slowly accumulates mycobacteria...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-12-01
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Series: | Pathogens |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-0817/10/12/1572 |