Anastrozole monotherapy further improves near-adult height after the initial combined treatment with leuprorelin and anastrozole in early-maturing girls with compromised growth prediction: results from the second phase of the GAIL study

Anastrozole monotherapy further improves near-adult height after the initial combined treatment with leuprorelin and anastrozole in early-maturing girls with compromised growth prediction: results from the second phase of the GAIL study

BackgroundThe first phase of the GAIL study (“Girls treated with an Aromatase Inhibitor and Leuprorelin,” ISRCTN11469487) has shown that the combination of anastrozole and leuprorelin for 24 months is safe and effective in improving the predicted adult height (PAH) in girls with early puberty and co...

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Bibliographic Details
Main Authors: Dimitrios T. Papadimitriou, Eleni Dermitzaki, Panagiotis Christopoulos, Sarantis Livadas, Ioanna N. Grivea, George Mastorakos
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Endocrinology
Subjects:
aromatase inhibitors
anastrozole
early puberty
precocious puberty
adult height
LHRH analogue
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1366970/full

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https://www.frontiersin.org/articles/10.3389/fendo.2024.1366970/full

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