Characterization of Plasmodium vivax Proteins in Plasma-Derived Exosomes From Malaria-Infected Liver-Chimeric Humanized Mice

Characterization of Plasmodium vivax Proteins in Plasma-Derived Exosomes From Malaria-Infected Liver-Chimeric Humanized Mice

Exosomes are extracellular vesicles of endocytic origin containing molecular signatures implying the cell of origin; thus, they offer a unique opportunity to discover biomarkers of disease. Plasmodium vivax, responsible for more than half of all malaria cases outside Africa, is a major obstacle in t...

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Bibliographic Details
Main Authors: Melisa Gualdrón-López, Erika L. Flannery, Niwat Kangwanrangsan, Vorada Chuenchob, Dietmar Fernandez-Orth, Joan Segui-Barber, Felix Royo, Juan M. Falcón-Pérez, Carmen Fernandez-Becerra, Marcus V. G. Lacerda, Stefan H. I. Kappe, Jetsumon Sattabongkot, Juan R. Gonzalez, Sebastian A. Mikolajczak, Hernando A. del Portillo
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Microbiology
Subjects:
Plasmodium vivax
hypnozoite
exosome
proteomics
biomarker
humanized mice
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01271/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.01271/full

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