PGC-1α determines light damage susceptibility of the murine retina.

The peroxisome proliferator-activated receptor γ coactivator 1 (PGC-1) proteins are key regulators of cellular bioenergetics and are accordingly expressed in tissues with a high energetic demand. For example, PGC-1α and PGC-1β control organ function of brown adipose tissue, heart, brain, liver and s...

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Main Authors: Anna Egger, Marijana Samardzija, Vithiyanjali Sothilingam, Naoyuki Tanimoto, Christina Lange, Silvia Salatino, Lei Fang, Marina Garcia-Garrido, Susanne Beck, Michal J Okoniewski, Albert Neutzner, Mathias W Seeliger, Christian Grimm, Christoph Handschin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22348062/pdf/?tool=EBI