Cuprizone feed formulation influences the extent of demyelinating disease pathology

Cuprizone feed formulation influences the extent of demyelinating disease pathology

Abstract Cuprizone is a copper-chelating agent that induces pathology similar to that within some multiple sclerosis (MS) lesions. The reliability and reproducibility of cuprizone for inducing demyelinating disease pathology depends on the animals ingesting consistent doses of cuprizone. Cuprizone-c...

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Bibliographic Details
Main Authors: Lillian M. Toomey, Melissa Papini, Brittney Lins, Alexander J. Wright, Andrew Warnock, Terence McGonigle, Sarah C. Hellewell, Carole A. Bartlett, Chidozie Anyaegbu, Melinda Fitzgerald
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-01963-3

Internet

https://doi.org/10.1038/s41598-021-01963-3

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