Extracellular Matrix Profiling and Disease Modelling in Engineered Vascular Smooth Muscle Cell Tissues

Extracellular Matrix Profiling and Disease Modelling in Engineered Vascular Smooth Muscle Cell Tissues

Aortic smooth muscle cells (SMCs) have an intrinsic role in regulating vessel homeostasis and pathological remodelling. In two-dimensional (2D) cell culture formats, however, SMCs are not embedded in their physiological extracellular matrix (ECM) environment. To overcome the limitations of conventio...

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Bibliographic Details
Main Authors: Ella Reed, Adam Fellows, Ruifang Lu, Marieke Rienks, Lukas Schmidt, Xiaoke Yin, Elisa Duregotti, Mona Brandt, Susanne Krasemann, Kristin Hartmann, Javier Barallobre-Barreiro, Owen Addison, Friederike Cuello, Arne Hansen, Manuel Mayr
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Matrix Biology Plus
Subjects:
Tissue engineering
3D cell culture
Proteomics
Smooth muscle cells
ECM
Calcification
Online Access:http://www.sciencedirect.com/science/article/pii/S2590028522000229

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http://www.sciencedirect.com/science/article/pii/S2590028522000229

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