Drosophila strain specific response to cisplatin neurotoxicity

Drosophila melanogaster has recently been developed as a simple, in vivo, genetic model of chemotherapy-induced peripheral neuropathy. Flies treated with the chemotherapy agent cisplatin display both a neurodegenerative phenotype and cell death in rapidly dividing follicles, mimicking the cell speci...

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Bibliographic Details
Main Authors: Christopher M. Groen, Jewel L. Podratz, Kevin Treb, Anthony J. Windebank
Format: Article
Language:English
Published: Taylor & Francis Group 2018-10-01
Series:Fly
Subjects:
Online Access:http://dx.doi.org/10.1080/19336934.2019.1565257