Precise modification of the surface charge of antigen enhances vaccine immunogenicity

Precise modification of the surface charge of antigen enhances vaccine immunogenicity

Aluminum (alum) adjuvant is the most extensively used protein subunit vaccine adjuvant, and its effectiveness and safety have been widely recognized. The surface charge of the antigen determines its electrostatic adsorption to alum adjuvant, which directly affects the immune efficacy of the protein...

Full description

Bibliographic Details
Main Authors: Xiaodong Zai, Zhiling Zhang, Chuge Zhou, Fangxin Zhao, Yue Zhang, Xiaolin Wang, Ruihua Li, Yaohui Li, Xiaofan Zhao, Shuyi Wang, Yilong Yang, Ying Yin, Jun Zhang, Junjie Xu, Wei Chen
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:The Innovation
Online Access:http://www.sciencedirect.com/science/article/pii/S2666675823000796

Similar Items

Similar Items