In vitro and in silico antibacterial evaluation of nitrocatechol chalcone and pyrazoline derivatives

In vitro and in silico antibacterial evaluation of nitrocatechol chalcone and pyrazoline derivatives

The aim of this study was to determine the in vitro antibacterial activity of nitrocatechol chalcone and pyrazoline derivatives previously synthesised by our research group against Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii and Klebsiella aerogenes, and to create and valid...

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Bibliographic Details
Main Authors: Alize Hoepfner, Anél Petzer, Jacobus P. Petzer, Judey Pretorius, Theunis T. Cloete
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Results in Chemistry
Subjects:
Drug repurposing
Nitrocatechol
Chalcone
Pyrazoline
Antibacterial activity
Common feature pharmacophore modelling
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715623004332

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http://www.sciencedirect.com/science/article/pii/S2211715623004332

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