Process induced degradation of carbamazepine during hot melt extrusion
The aim of this study was to evaluate hot melt extrudates of carbamazepine (CBZ) for presence of process induced degradation product iminostilbene (IMB) and quantifying using high performance liquid chromatography (HPLC). CBZ was used as model drug. Hot-melt extrusion (HME) was performed to prepare...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
University of Huddersfield Press
2023-12-01
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Series: | British Journal of Pharmacy |
Subjects: | |
Online Access: | https://www.bjpharm.org.uk/article/1392/galley/1025/view/ |