Synthesis of acyl-hydrazone from usnic acid and isoniazid and its anti-Mycobacterium tuberculosis activity

Compound usnic acid (1), isolated from lichen Evernia prunastri (Cajamarca-Peru) and the synthesis and characterization of its acyl-hydrazone (2), from the condensation reaction between usnic acid and isoniazid in an ethanol solution under reflux, giving an overall yield of 95%, were evaluated. Both...

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Bibliographic Details
Main Authors: Melissa Barrera Tomas, Gloria Eva Tomas Chota, Patricia Sheen Cortavarría, Patricia Fuentes Bonilla, Miguel Angel Inocente Camones, Julio Cesar Santiago Contreras
Format: Article
Language:English
Published: Universidad Nacional de Colombia 2017-09-01
Series:Revista Colombiana de Química
Subjects:
Online Access:https://revistas.unal.edu.co/index.php/rcolquim/article/view/61980