Large-scale production of lentiviral vector in a closed system hollow fiber bioreactor

Large-scale production of lentiviral vector in a closed system hollow fiber bioreactor

Lentiviral vectors are widely used in the field of gene therapy as an effective method for permanent gene delivery. While current methods of producing small scale vector batches for research purposes depend largely on culture flasks, the emergence and popularity of lentiviral vectors in translationa...

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Bibliographic Details
Main Authors: Jonathan Sheu, Jim Beltzer, Brian Fury, Katarzyna Wilczek, Steve Tobin, Danny Falconer, Jan Nolta, Gerhard Bauer
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Molecular Therapy: Methods & Clinical Development
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050116300328

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http://www.sciencedirect.com/science/article/pii/S2329050116300328

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