A genetic screen to discover SUMOylated proteins in living mammalian cells

Abstract Post-translational modification by the Small Ubiquitin-related Modifier (SUMO) is indispensable for diverse biological mechanisms. Although various attempts have been made to discover novel SUMO substrate proteins to unveil the roles of SUMOylation, the reversibility of SUMOylation, and the...

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Bibliographic Details
Main Authors: Maki Komiya, Akihiro Ito, Mizuki Endo, Daisuke Hiruma, Mitsuru Hattori, Hisato Saitoh, Minoru Yoshida, Takeaki Ozawa
Format: Article
Language:English
Published: Nature Portfolio 2017-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-17450-7