Copper-Containing Nanoparticles and Organic Complexes: Metal Reduction Triggers Rapid Cell Death via Oxidative Burst

Copper-Containing Nanoparticles and Organic Complexes: Metal Reduction Triggers Rapid Cell Death via Oxidative Burst

Copper-containing agents are promising antitumor pharmaceuticals due to the ability of the metal ion to react with biomolecules. In the current study, we demonstrate that inorganic Cu<sup>2+</sup> in the form of oxide nanoparticles (NPs) or salts, as well as Cu ions in the context of org...

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Bibliographic Details
Main Authors: Sergey A. Tsymbal, Anna A. Moiseeva, Nikol A. Agadzhanian, Svetlana S. Efimova, Alina A. Markova, Dmitry A. Guk, Olga O. Krasnovskaya, Victoria M. Alpatova, Andrei V. Zaitsev, Anna V. Shibaeva, Victor V. Tatarskiy, Marina S. Dukhinova, Valentina A. Ol’shevskaya, Olga S. Ostroumova, Elena K. Beloglazkina, Alexander A. Shtil
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
copper
reactive oxygen species
redox potential
drug resistance
cell death
tumor cells
Online Access:https://www.mdpi.com/1422-0067/22/20/11065

Internet

https://www.mdpi.com/1422-0067/22/20/11065

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