The mitochondrial succinate dehydrogenase complex controls the STAT3-IL-10 pathway in inflammatory macrophages

The mitochondrial succinate dehydrogenase complex controls the STAT3-IL-10 pathway in inflammatory macrophages

Summary: The functions of macrophages are tightly regulated by their metabolic state. However, the role of the mitochondrial electron transport chain (ETC) in macrophage functions remains understudied. Here, we provide evidence that the succinate dehydrogenase (SDH)/complex II (CII) is required for...

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Bibliographic Details
Main Authors: Dino Gobelli, Pablo Serrano-Lorenzo, María J. Esteban-Amo, Julia Serna, M. Teresa Pérez-García, Antonio Orduña, Alexis A. Jourdain, Miguel Á. Martín-Casanueva, Miguel Á. de la Fuente, María Simarro
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:iScience
Subjects:
Biological sciences
Molecular biology
Immunology
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422301550X

Internet

http://www.sciencedirect.com/science/article/pii/S258900422301550X

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