Optimal serotype compositions for Pneumococcal conjugate vaccination under serotype replacement.

Pneumococcal conjugate vaccination has proved highly effective in eliminating vaccine-type pneumococcal carriage and disease. However, the potential adverse effects of serotype replacement remain a major concern when implementing routine childhood pneumococcal conjugate vaccination programmes. Apply...

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Bibliographic Details
Main Authors: Markku Nurhonen, Kari Auranen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-02-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3923658?pdf=render