In vitro and in vivo cytotoxicity of troglitazone in pancreatic cancer

Abstract Background Troglitazone (TGZ) is a peroxisome proliferator-activated receptor gamma (PPARγ) agonist that has been investigated as a potential chemopreventive and chemotherapeutic agent. However, the antitumor efficacy and mechanisms of TGZ in pancreatic cancer have not been extensively inve...

Full description

Bibliographic Details
Main Authors: Megumi Fujita, Ai Hasegawa, Motohiro Yamamori, Noboru Okamura
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13046-017-0557-6