Overexpression of chaperonin containing T-complex polypeptide subunit zeta 2 (CCT6b) suppresses the functions of active fibroblasts in a rat model of joint contracture

Overexpression of chaperonin containing T-complex polypeptide subunit zeta 2 (CCT6b) suppresses the functions of active fibroblasts in a rat model of joint contracture

Abstract Background Joint contracture is a fibrous disease characterized as joint capsule fibrosis that results in joint dysfunction and disability. The purpose of this study was to analyze the biological activities of chaperonin containing T-complex polypeptide (CCT) subunits and to determine the r...

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Bibliographic Details
Main Authors: Xiaoyou Yi, Zhe Wang, Jianhua Ren, Ze Zhuang, Kaihua Liu, Kun Wang, Ronghan He
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Chaperonin
CCT6b
CCT7
Anti-fibrosis
Joint contracture
Online Access:http://link.springer.com/article/10.1186/s13018-019-1161-6

Internet

http://link.springer.com/article/10.1186/s13018-019-1161-6

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