Nitric oxide signaling through three receptors regulates virulence, biofilm formation, and phenotypic heterogeneity of Legionella pneumophila

ABSTRACT The causative agent of Legionnaires’ disease, Legionella pneumophila, is an environmental bacterium, that replicates in macrophages, parasitizes amoeba, and forms biofilms. L. pneumophila employs the Legionella quorum sensing (Lqs) system and the transcription factor LvbR to control various...

Full description

Bibliographic Details
Main Authors: Sarah Michaelis, Tong Chen, Camille Schmid, Hubert Hilbi
Format: Article
Language:English
Published: American Society for Microbiology 2024-06-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.00710-24