Mice lacking DIO3 exhibit sex-specific alterations in circadian patterns of corticosterone and gene expression in metabolic tissues

Abstract Disruption of circadian rhythms is associated with neurological, endocrine and metabolic pathologies. We have recently shown that mice lacking functional type 3 deiodinase (DIO3), the enzyme that clears thyroid hormones, exhibit a phase shift in locomotor activity, suggesting altered circad...

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Bibliographic Details
Main Authors: Zhaofei Wu, M. Elena Martinez, Arturo Hernandez
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Molecular and Cell Biology
Subjects:
Online Access:https://doi.org/10.1186/s12860-024-00508-6