Associations of the vasoactive peptides CT-proET-1 and MR-proADM with incident type 2 diabetes: results from the BiomarCaRE Consortium

Associations of the vasoactive peptides CT-proET-1 and MR-proADM with incident type 2 diabetes: results from the BiomarCaRE Consortium

Abstract Background Endothelin-1 (ET-1) and adrenomedullin (ADM) are commonly known as vasoactive peptides that regulate vascular homeostasis. Less recognised is the fact that both peptides could affect glucose metabolism. Here, we investigated whether ET-1 and ADM, measured as C-terminal-proET-1 (C...

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Main Authors: Chaterina Sujana, Veikko Salomaa, Frank Kee, Jochen Seissler, Pekka Jousilahti, Charlotte Neville, Cornelia Then, Wolfgang Koenig, Kari Kuulasmaa, Jaakko Reinikainen, Stefan Blankenberg, Tanja Zeller, Christian Herder, Ulrich Mansmann, Annette Peters, Barbara Thorand, for the BiomarCaRE Consortium
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Cardiovascular Diabetology
Subjects:
Adrenomedullin
C-terminal-proendothelin-1
Endothelin-1
Epidemiology
Incident type 2 diabetes
Mendelian randomisation
Online Access:https://doi.org/10.1186/s12933-022-01513-9

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https://doi.org/10.1186/s12933-022-01513-9

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