Changes of Ovarian microRNA Profile in Long-Living Ames Dwarf Mice during Aging.

The Ames dwarf (df/df) mice have extended longevity and can preserve the ovarian reserve longer than Normal (N) mice. Based on this, the aim of our study was to evaluate the ovarian microRNA (miRNA) profile in young and aged df/df and N mice. Ovarian tissue was collected at 5-6 months and at 21-22 m...

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Bibliographic Details
Main Authors: Augusto Schneider, Scot J Matkovich, Berta Victoria, Lina Spinel, Andrzej Bartke, Pawel Golusinski, Michal M Masternak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5207734?pdf=render