SIRT1 gene polymorphisms affect the protein expression in cardiovascular diseases.

Cardiovascular disease (CVD), the leading cause of death worldwide, is related to gene-environment interactions due to epigenetic factors. SIRT1 protein and its downstream pathways are critical for both normal homeostasis and protection from CVD-induced defects. The aim of this study was to investig...

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Bibliographic Details
Main Authors: Ulkan Kilic, Ozlem Gok, Ahmet Bacaksiz, Muzeyyen Izmirli, Birsen Elibol-Can, Omer Uysal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3938716?pdf=render