Fatty acid binding protein 4 and 5 play a crucial role in thermogenesis under the conditions of fasting and cold stress.

Hypothermia is rapidly induced during cold exposure when thermoregulatory mechanisms, including fatty acid (FA) utilization, are disturbed. FA binding protein 4 (FABP4) and FABP5, which are abundantly expressed in adipose tissues and macrophages, have been identified as key molecules in the pathogen...

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Main Authors: Mas Rizky A A Syamsunarno, Tatsuya Iso, Aiko Yamaguchi, Hirofumi Hanaoka, Mirasari Putri, Masaru Obokata, Hiroaki Sunaga, Norimichi Koitabashi, Hiroki Matsui, Kazuhisa Maeda, Keigo Endo, Yoshito Tsushima, Tomoyuki Yokoyama, Masahiko Kurabayashi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24603714/pdf/?tool=EBI