RNA-seq and ChIP-seq Identification of Unique and Overlapping Targets of GLI Transcription Factors in Melanoma Cell Lines

RNA-seq and ChIP-seq Identification of Unique and Overlapping Targets of GLI Transcription Factors in Melanoma Cell Lines

Background: Despite significant progress in therapy, melanoma still has a rising incidence worldwide, and novel treatment strategies are needed. Recently, researchers have recognized the involvement of the Hedgehog-GLI (HH-GLI) signaling pathway in melanoma and its consistent crosstalk with the MAPK...

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Bibliographic Details
Main Authors: Matea Kurtović, Nikolina Piteša, Nenad Bartoniček, Petar Ozretić, Vesna Musani, Josipa Čonkaš, Tina Petrić, Cecile King, Maja Sabol
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cancers
Subjects:
melanoma
HH-GLI pathway
GLI targets
MAPK pathway
targeted therapy
Online Access:https://www.mdpi.com/2072-6694/14/18/4540

Internet

https://www.mdpi.com/2072-6694/14/18/4540

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