Asexual Blood-Stage Malaria Vaccine Candidate PfRipr5: Enhanced Production in Insect Cells

Asexual Blood-Stage Malaria Vaccine Candidate PfRipr5: Enhanced Production in Insect Cells

The malaria asexual blood-stage antigen PfRipr and its most immunogenic fragment PfRipr5 have recently risen as promising vaccine candidates against this infectious disease. Continued development of high-yielding, scalable production platforms is essential to advance the malaria vaccine research. In...

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Bibliographic Details
Main Authors: Ricardo Correia, Bárbara Fernandes, Rute Castro, Hikaru Nagaoka, Eizo Takashima, Takafumi Tsuboi, Akihisa Fukushima, Nicola K. Viebig, Hilde Depraetere, Paula M. Alves, António Roldão
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
malaria asexual blood-stage vaccine
PfRipr5
insect cells
baculovirus expression vector system
low temperature
improved production
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.908509/full

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https://www.frontiersin.org/articles/10.3389/fbioe.2022.908509/full

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