Regulation and Functional Significance of 5-Hydroxymethylcytosine in Cancer
Epigenetic modes of gene regulation are important for physiological conditions and its aberrant changes can lead to disease like cancer. 5-hydroxymethylcytosine (5hmC) is an oxidized form of 5-methylcytosine (5mC) catalyzed by Ten Eleven Translocation (TET) enzymes. 5hmC is considered to be a demeth...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2017-11-01
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Series: | Epigenomes |
Subjects: | |
Online Access: | https://www.mdpi.com/2075-4655/1/3/19 |