Regulation and Functional Significance of 5-Hydroxymethylcytosine in Cancer

Epigenetic modes of gene regulation are important for physiological conditions and its aberrant changes can lead to disease like cancer. 5-hydroxymethylcytosine (5hmC) is an oxidized form of 5-methylcytosine (5mC) catalyzed by Ten Eleven Translocation (TET) enzymes. 5hmC is considered to be a demeth...

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Bibliographic Details
Main Authors: Vittal Rangan Arvinden, Arunagiri Kuha Deva Magendhra Rao, Thangarajan Rajkumar, Samson Mani
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Epigenomes
Subjects:
Online Access:https://www.mdpi.com/2075-4655/1/3/19