Tumor microenvironments self-activated nanoscale metal-organic frameworks for ferroptosis based cancer chemodynamic/photothermal/chemo therapy

Tumor microenvironments self-activated nanoscale metal-organic frameworks for ferroptosis based cancer chemodynamic/photothermal/chemo therapy

Ferroptosis, as a newly discovered cell death form, has become an attractive target for precision cancer therapy. Several ferroptosis therapy strategies based on nanotechnology have been reported by either increasing intracellular iron levels or by inhibition of glutathione (GSH)-dependent lipid hyd...

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Bibliographic Details
Main Authors: Yu Liang, Li Zhang, Chao Peng, Shiyu Zhang, Siwen Chen, Xin Qian, Wanxian Luo, Qing Dan, Yongyan Ren, Yingjia Li, Bingxia Zhao
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Ferroptosis
Tumor microenvironments
Fenton reaction
Metal-organic frameworks (MOFs)
GSH depletion
Drug delivery
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383521000198

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http://www.sciencedirect.com/science/article/pii/S2211383521000198

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